Amylin antibody , Cat. # FNab00384

SKU: FNab00384

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic ?-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Immunogen:islet amyloid polypeptide

Synonyms:Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide

Observed MW:10 kDa

Uniprot ID:P10997

Reactivity:Human

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:3375

Research Area:Signal Transduction