alpha-synuclein antibody , Cat. # FNab09891

SKU: FNab09891

Size:100ug

Purification:protein A+G purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:5C6

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

Immunogen:synuclein, alpha (non A4 component of amyloid precursor)

Synonyms:Alpha synuclein, NACP, PARK1, PARK4, SNCA

Observed MW:18 kDa

Uniprot ID:P37840

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000

Gene ID:6622

Research Area:Neuroscience