ALKBH1 Polyclonal Antibody

SKU: E-AB-10699

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ALKBH1

Target Synonym: ABH;ABH1;alkB;alkB homolog 1 histone H2A dioxygenase;AlkB;alkylation repair homolog 1 (E. coli);ALKB1;ALKBH;ALKBH1;Alkylated DNA repair protein alkB homolog 1;Alkylation repair homolog 1;Alkylation repair;alkB homolog;Alpha-ketoglutarate-dependent dioxygenase ABH1;DNA lyase ABH1;DNA oxidative demethylase ALKBH1;hABH

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13686

Accession:

Background: This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human ALKBH1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 44kDa

ObservedMW: