ALKBH1 Antibody - Cat. #: CSB-PA614439ESR2HU

SKU: CSB-PA614439ESR2HU

Size :50ul

Clone Number:

Aliases:ABH antibody; ABH1 antibody; alkB antibody; alkB homolog 1 histone H2A dioxygenase antibody; AlkB; alkylation repair homolog 1 (E. coli) antibody; ALKB1_HUMAN antibody; ALKBH antibody; ALKBH1 antibody; Alkylated DNA repair protein alkB homolog 1 antibody; Alkylation repair homolog 1 antibody; Alkylation repair; alkB homolog antibody; Alpha-ketoglutarate-dependent dioxygenase ABH1 antibody; DNA lyase ABH1 antibody; DNA oxidative demethylase ALKBH1 antibody; hABH antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13686

Immunogen:Recombinant Human Alkylated DNA repair protein alkB homolog 1 protein (110-389AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background:Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ALKBH1

Research Areas:Epigenetics and Nuclear Signaling