AGRIN Polyclonal Antibody

SKU: BT-AP14147

Size:100μL

Background:This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ)| as identified in mouse knock-out studies. The encoded protein contains several laminin G| Kazal type serine protease inhibitor| and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles| a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Neuroscience

Target_protein:AGRN

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Agrin

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O00468; Mouse: A2ASQ1; Rat: P25304

Synonyms:Agrin

GeneID:Human: 375790