AF/LE Purified Anti-Mouse CD51 Antibody[RMV-7]

SKU: GBS-F12350

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD51

Target Synonym:Itgav,Integrin alpha-V,Integrin αV chain,Vitronectin Receptor,αV integrin,vitronectin R, integrin &alpha-V-V

Research Areas:

Conjugation:None (AF/LE)

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG1,κ

Clonality:Monoclonal

Clone NO.:RMV-7

UNIProt ID:P43406

Background:CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αv integrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse CD51 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID: