AF/LE Purified Anti-Human CD19 Antibody[HIB19]

SKU: AN008610

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD19

Target Synonym:CVID;B-lymphocyteantigenCD;B-lymphocyte antigen CD;T-cellsurfaceantigenLeu;Differentiation antigen CD;T-cell surface antigen Leu;B-lymphocytesurfaceantigenB;B-lymphocyte surface antigen B;B4;CVID3;CD19;B-lymphocyteantigenCD19;B-lymphocytesurfaceantigenB4;T-cellsurfaceantigenLeu-12;B-lymphocyte antigen CD19;B-lymphocyte surface antigen B4;Differentiation antigen CD19;T-cell surface antigen Leu-12;B4;CVID3;CD19;CD19 molecule

Research Areas:Immunology;Stem Cells

Conjugation:None (AF/LE)

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:HIB19

UNIProt ID:P15391

Background:CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity matuRation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD19 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:930