ADHX Polyclonal Antibody

SKU: BT-AP06085

Size:100μL

Background:This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde| a potent irritant and sensitizing agent that causes lacrymation| rhinitis| pharyngitis| and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Research_area:Signal transduction; Metabolism

Target_protein:ADH5

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Alcohol dehydrogenase class-3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P11766; Mouse: P28474; Rat: P12711

Synonyms:Alcohol dehydrogenase class-3 ;EC 1.1.1.1;Alcohol dehydrogenase 5;Alcohol dehydrogenase class chi chain;Alcohol dehydrogenase class-III;Glutathione-dependent formaldehyde dehydrogenase;FALDH

GeneID:Human: 128