ADA22 Polyclonal Antibody

SKU: BT-AP14128

Size:100μL

Background:This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. Unlike other members of the ADAM protein family| the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice| it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Research_area:Signal transduction; Cell biology

Target_protein:ADAM22

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Disintegrin and metalloproteinase domain-containing protein 22

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9P0K1; Mouse: Q9R1V6

Synonyms:Disintegrin and metalloproteinase domain-containing protein 22 ;ADAM 22;Metalloproteinase-disintegrin ADAM22-3;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 2

GeneID:Human: 53616