ACTN4 Polyclonal Antibody

SKU: E-AB-14759

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ACTN4

Target Synonym: actinin 4;Actinin alpha 4;actinin4;ACTN 4;ACTN4;ACTN4;Alpha-actinin-4;DKFZp686K23158;F actin cross linking protein;F-actin cross-linking protein;Focal segmental glomerulosclerosis 1;FSGS 1;FSGS;FSGS1;Non muscle alpha actinin 4;Non-muscle alpha-actinin 4

Research Areas: Cancer;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O43707

Accession:

Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.

Concentration: 0.8 mg/mL

Immunogen: Recombinant protein of human ACTN4

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 105kDa

ObservedMW: