ACTN1 Polyclonal Antibody

SKU: E-AB-70225

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ACTN1

Target Synonym:actinin 1 smooth muscle;Actinin alpha 1;actinin;alpha 1;ACTN 1;Actn1;ACTN1;Alpha Actinin 1;Alpha actinin cytoskeletal isoform;Alpha-actinin cytoskeletal isoform;Alpha-actinin-1;BDPLT15;F actin cross linking protein;F-actin cross-linking protein;FLJ40884;FLJ54432;Non muscle alpha actinin 1;Non-muscle alpha-actinin-1

Research Areas:Cancer;Developmental Biology;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P12814,Q7TPR4,Q9Z1P2

Accession:

Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Concentration:0.66 mg/mL

Immunogen:Recombinant protein corresponding to Mouseα-actinin1

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:1000-1:3000

Calculated MW:102-107kDa

ObservedMW:110kDa