ACTL6B Polyclonal Antibody

SKU: E-AB-19033

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ACTL6B

Target Synonym: 53 kDa BRG1 associated factor B;53 kDa BRG1-associated factor B;ACL 6B;ACL6B;ACL6B;Actin like 6;Actin like protein 6B;Actin like protein6B;Actin related protein;Actin related protein Baf53b;actin-like 6B;Actin-like protein 6B;Actin-related protein Baf53b;Actl 6;ACTL 6B;Actl6;ACTL6 B;Actl6b;Arp Na;ArpN a;ArpN alpha;ArpNa;ArpNalpha;Baf 53b;BAF53B;BRG1-associated factor 53B

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Neuroscience;Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O94805

Accession:

Background: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

Concentration: 1.74 mg/mL

Immunogen: Fusion protein of human ACTL6B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:50-1:300

Calculated MW: 47 kDa

ObservedMW: Refer to figures