Actin-alpha/ gamma Polyclonal Antibody

SKU: BT-AP06032

Size:100μL

Background:Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms| alpha| beta| and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Research_area:Cardiovascular; Signal transduction

Target_protein:ACTC1

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Actin alpha cardiac muscle 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):41737;41793

UniProt accession:Human: P68032/P63261/P63267/P68133; Rat: P68035/P63259/P63269/P68136

Synonyms:Actin alpha cardiac muscle 1; ACTC1; ACTC; Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ACTG1; ACTB; ACTG; Actin; cytoplasmic 2; Gamma-actin; ACTG2; ACTA3; ACTL3; ACTSG; Actin; gamma-enteric smooth muscle; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin;

GeneID:Human: 58/70/71/72; Mouse: 11464/11465/11468/11459; Rat: 29275/100361457/25365/29437