2AAA Polyclonal Antibody

SKU: BT-AP08343

Size:100μL

Background:This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases| and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme| which is composed of a catalytic subunit and a constant regulatory subunit| that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Research_area:Signal transduction; Cell biology

Target_protein:PPP2R1A

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P30153; Mouse: Q76MZ3

Synonyms:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform ;Medium tumor antigen-associated 61 kDa protein;PP2A subunit A isoform PR65-alpha;PP2A subunit A isoform R1-alpha

GeneID:Human: 5518