ZO1 rabbit pAb

SKU: ES10356

Size: 100μL

Source:Rabbit

Applications:WB;IF;ELISA

Reactivity:Human;Mouse

Dilution:WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from part region of human protein.AA1600-1700

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):192kD

Human_gene_id:7082

Human_swiss_prot_no:Q07157

Subcellular_location:Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, tight junction . Cell junction . Cell junction, gap junction. Cell projection, podosome . Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact (PubMed:7798316). At podosomal sites, is predominantly localized in the ring structure surrounding the actin core (PubMed:20930113). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:31473225). .

Other_name:

Background:This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014],