ZnT-8 Polyclonal Antibody

SKU: BT-AP09752

Size:100μL

Background:Zinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.

Research_area:Signal Transduction; Metabolism

Target_protein:SLC30A8

applications:WB, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:ZnT-8 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):40729

UniProt accession:Human: Q8IWU4; Mouse: Q8BGG0

Synonyms:SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

GeneID:Human: 169026