ZIP kinase antibody , Cat. # FNab09640

SKU: FNab09640

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:ZIP kinase, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. ZIP kinase is a Serine/threonine kinase which acts as a positive regulator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein.

Immunogen:death-associated protein kinase 3

Synonyms:DAP kinase 3, DAP like kinase, DAPK3, Dlk, ZIP kinase, ZIPK

Observed MW:53kd

Uniprot ID:O43293

Reactivity:Human

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:200-1:1000; IF: 1:20-1:200

Gene ID:

Research Area: