ZC3H8 antibody , Cat. # FNab09605

SKU: FNab09605

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region(IRR) of the GATA3 gene(By similarity). Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Immunogen:zinc finger CCCH-type containing 8

Synonyms:Fliz1, ZC3H8, ZC3HDC8

Observed MW:34 kDa

Uniprot ID:Q8N5P1

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:1000-1:10000

Gene ID:84524

Research Area:Metabolism