XPC Monoclonal Antibody

SKU: BT-MCA3924

Size:100μL

Background:The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:XPC

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5F4B11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:XPC

Immunogen:Purified recombinant fragment of human XPC (AA: 32-133) expressed in mammalian.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):106kDa

UniProt accession:Q01831

Synonyms:XP3, RAD4, XPCC, p125

GeneID:7508