WNT1 Antibody - Cat. #: CSB-PA586979

SKU: CSB-PA586979

Size :50ul

Clone Number:

Aliases:BMND16 antibody; INT1 antibody; OI15 antibody; oncogene Int1 antibody; Proto oncogene protein Wnt 1 antibody; Proto-oncogene Int-1 homolog antibody; Proto-oncogene Wnt-1 antibody; Wingless type MMTV integration site family member 1 antibody; wingless-type MMTV integration site family; member 1 (oncogene INT1) antibody; Wnt 1 antibody; wnt1 antibody; WNT1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P04628

Immunogen:Synthetic peptide of Human WNT1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WNT1

Research Areas:Cancer;Stem cells