WDR77 Antibody, HRP conjugated - Cat. #: CSB-PA859030LB01HU

SKU: CSB-PA859030LB01HU

Size :50ug

Clone Number:

Aliases:2610312E17Rik antibody; Androgen receptor cofactor p44 antibody; C79984 antibody; HKMT1069 antibody; MEP 50 antibody; MEP-50 antibody; MEP50 antibody; MEP50_HUMAN antibody; Methylosome protein 50 antibody; MGC2722 antibody; Nbla10071 antibody; p44 antibody; p44/Mep50 antibody; RGD1310479 antibody; RP11 552M11.3 antibody; WD repeat containing protein 77 antibody; WD repeat domain 77 antibody; WD repeat-containing protein 77 antibody; WDR77 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BQA1

Immunogen:Recombinant Human Methylosome protein 50 protein (1-312AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WDR77

Research Areas:Epigenetics and Nuclear Signaling; Signal transduction