WAC Antibody, HRP conjugated - Cat. #: CSB-PA861133HB01HU

SKU: CSB-PA861133HB01HU

Size :50ug

Clone Number:

Aliases:1110067P07Rik antibody; BA48B24 antibody; BA48B24.1 antibody; BM 016 antibody; FLJ31290 antibody; KIAA1844 antibody; MGC10753 antibody; OTTHUMP00000019380 antibody; OTTHUMP00000019382 antibody; PRO1741 antibody; wac antibody; WAC_HUMAN antibody; WW domain containing adapter protein with coiled coil antibody; WW domain containing adaptor with coiled coil antibody; WW domain-containing adapter protein with coiled-coil antibody; Wwp4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BTA9

Immunogen:Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Acts as a linker between gene transcription and histone H2B monoubiquitination at \\\'Lys-120\\\' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:WAC

Research Areas:Cell biology