Vinculin antibody , Cat. # FNab09800

SKU: FNab09800

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:5E7

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific.

Immunogen:vinculin

Synonyms:CMD1W, Metavinculin, MVCL, VCL, Vinculin

Observed MW:124 kDa

Uniprot ID:P18206

Reactivity:Human, Rat, Mouse

Tested Application:ELISA, FC, IF, IHC, WB

Recommended dilution:WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500

Gene ID:

Research Area:Immunology, Cardiovascular