USP14 Antibody, Biotin conjugated - Cat. #: CSB-PA025704LD01HU

SKU: CSB-PA025704LD01HU

Size :50ug

Clone Number:

Aliases:Deubiquitinating enzyme 14 antibody; TGT antibody; tRNA guanine transglycosylase 60 kD subunit antibody; tRNA guanine transglycosylase antibody; Ubiquitin carboxyl terminal hydrolase 14 antibody; Ubiquitin carboxyl-terminal hydrolase 14 antibody; Ubiquitin specific peptidase 14 antibody; Ubiquitin specific processing protease 14 antibody; Ubiquitin specific protease 14 antibody; Ubiquitin thiolesterase 14 antibody; Ubiquitin-specific-processing protease 14 antibody; UBP14_HUMAN antibody; USP 14 antibody; USP14 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P54578

Immunogen:Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 protein (1-494AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:USP14

Research Areas:Epigenetics and Nuclear Signaling; Cell biology