USP1 antibody , Cat. # FNab09303

SKU: FNab09303

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8F7

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).

Immunogen:ubiquitin specific peptidase 1

Synonyms:Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1

Observed MW:90 kDa

Uniprot ID:O94782

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:1000-1:10000; IHC: 1:20-1:200

Gene ID:7398

Research Area:Epigenetics, Metabolism