USH2A rabbit pAb

SKU: ES12410

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human; Mouse;Rat

Dilution:IHC-p 1：50-200

Immunogen:Synthesized peptide derived from human USH2A AA range: 3731-3781

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:7399

Human_swiss_prot_no:O75445

Subcellular_location:Cell projection, stereocilium membrane ; Single-pass type I membrane protein . Component of the interstereocilia ankle links in the inner ear sensory cells. In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex. .; [Isoform 2]: Secreted.

Other_name:

Background:This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],