UFD2 rabbit pAb

SKU: ES4452

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from the Internal region of human UFD2.

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:10277

Human_swiss_prot_no:O95155

Subcellular_location:Cytoplasm . Nucleus .

Other_name:UBE4B; HDNB1; KIAA0684; UFD2; Ubiquitin conjugation factor E4 B; Homozygously deleted in neuroblastoma 1; Ubiquitin fusion degradation protein 2

Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],