UBE2C antibody , Cat. # FNab09166

SKU: FNab09166

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:7E3

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Immunogen:ubiquitin-conjugating enzyme E2C

Synonyms:DJ447F3.2, UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C

Observed MW:17 kDa

Uniprot ID:O00762

Reactivity:Human

Tested Application:ELISA, IF, IHC, WB

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID:11065

Research Area:Epigenetics, Metabolism