UBASH3B Antibody - Cat. #: CSB-PA840585ESR2HU

SKU: CSB-PA840585ESR2HU

Size :50ul

Clone Number:

Aliases:Cbl interacting protein p70 antibody; Cbl interacting protein Sts 1 antibody; Cbl interacting protein Sts1 antibody; Cbl-interacting protein p70 antibody; KIAA1959 antibody; MGC15437 antibody; Nm23 phosphorylated unknown substrate antibody; p70 antibody; SH3 domain containing 70 kDa protein antibody; Sts 1 antibody; STS-1 antibody; STS1 antibody; Suppressor of T cell receptor signaling 1 antibody; Suppressor of T-cell receptor signaling 1 antibody; T-cell ubiquitin ligand 2 antibody; TULA-2 antibody; Tyrosine-protein phosphatase STS1/TULA2 antibody; Ubash3b antibody; Ubiquitin associated and SH3 domain containing B antibody; Ubiquitin-associated and SH3 domain-containing protein B antibody; UBS3B_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TF42

Immunogen:Recombinant Human Ubiquitin-associated and SH3 domain-containing protein B protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:UBASH3B

Research Areas:Cell biology; Immunology; Signal transduction