UBA3 Rabbit Polyclonal Antibody

SKU: BT-AP13330

Size:100μL

Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes| or E1s| ubiquitin-conjugating enzymes| or E2s| and ubiquitin-protein ligases| or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1| an amyloid beta precursor protein binding protein| to form a heterodimer| and then the enzyme complex activates NEDD8| a ubiquitin-like protein| which regulates cell division| signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Cell biology

Target_protein:UBA3

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:UBA3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):50930

UniProt accession:Human: Q8TBC4; Mouse: Q8C878; Rat: Q99MI7

Synonyms:UBA3

GeneID:Human: 9039; Mouse: 22200; Rat: 117553