TULP3 antibody , Cat. # FNab09109

SKU: FNab09109

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A(IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide(phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.

Immunogen:tubby like protein 3

Synonyms:Tubby like protein 3, Tubby related protein 3, TUBL3, TULP3

Observed MW:56 kDa

Uniprot ID:O75386

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP, IF

Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200; IP: 1:200-1:1000; IF: 1:20-1:200

Gene ID:7289

Research Area:Neuroscience, Developmental biology