Tuberin(Phospho Thr1462) Polyclonal Antibody

SKU: BT-AP08238

Size:100μL

Background:Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Epigenetics and nuclear signaling; Cell biology; Signal transduction; Metabolism

Target_protein:TSC2

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Tuberin

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):200749

UniProt accession:Human: P49815; Mouse: Q61037; Rat: P49816

Synonyms:Tuberin; TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein

GeneID:Human: 7249; Rat: 24855