TSG101 Monoclonal Antibody

SKU: BT-MCA2048

Size:100μL

Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

Research_area:Cell Biology

Target_protein:TSG101

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:5H2A12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TSG101

Immunogen:Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):44kDa

UniProt accession:Q99816

Synonyms:TSG10, VPS23

GeneID:7251