TSC22D3 Antibody, HRP conjugated - Cat. #: CSB-PA860343LB01HU

SKU: CSB-PA860343LB01HU

Size :50ug

Clone Number:

Aliases:Delta sleep-inducing peptide immunoreactor antibody; DIP antibody; DSIP immunoreactive leucine zipper protein antibody; DSIP-immunoreactive peptide antibody; Dsip1 antibody; Dsipi antibody; GILZ antibody; Glucocorticoid-induced leucine zipper protein antibody; hDIP antibody; Protein DIP antibody; T22D3_HUMAN antibody; TSC-22-like protein antibody; TSC-22-related protein antibody; TSC-22R antibody; TSC22 domain family protein 3 antibody; TSC22 domain family, member 3 antibody; TSC22 related inducible leucine zipper 3 antibody; TSC22D3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99576

Immunogen:Recombinant Human TSC22 domain family protein 3 protein (58-134AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TSC22D3

Research Areas:Cell biology; Signal transduction