TRIP10 Antibody, HRP conjugated - Cat. #: CSB-PA624029LB01HU

SKU: CSB-PA624029LB01HU

Size :50ug

Clone Number:

Aliases:Cdc42 interacting protein 4 antibody; Cdc42 interaction protein 4 long isoform antibody; Cdc42-interacting protein 4 antibody; CG11341 antibody; CG15015 PA antibody; Cip 4 antibody; CIP4 antibody; CIP4_HUMAN antibody; DCIP4 antibody; hSTP antibody; Protein Felic antibody; Salt tolerant protein antibody; Salt tolerator antibody; STOT antibody; STP antibody; Thyroid hormone receptor interactor 10 antibody; Thyroid receptor interacting protein 10 antibody; Thyroid receptor-interacting protein 10 antibody; TR-interacting protein 10 antibody; TRIP 10 antibody; TRIP-10 antibody; trip10 antibody; Truncated Cdc42 interaction protein 4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15642

Immunogen:Recombinant Human Cdc42-interacting protein 4 protein (276-486AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TRIP10

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction