TRIM2 Rabbit Polyclonal Antibody

SKU: BT-AP05260

Size:100μL

Background:The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains| a RING| a B-box type 1 and a B-box type 2| and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling; Cell biology

Target_protein:TRIM2

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:TRIM2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):81840

UniProt accession:Human: Q9C040; Mouse: Q9ESN6; Rat: D3ZQG6

Synonyms:TRIM2

GeneID:Human: 23321; Mouse: 80890; Rat: 361970