TPM1 Antibody - Cat. #: CSB-PA047043

SKU: CSB-PA047043

Size :50ul

Clone Number:

Aliases:AA986836 antibody; AI854628 antibody; Alpha tropomyosin antibody; alpha-TM antibody; Alpha-tropomyosin antibody; C15orf13 antibody; cardiomyopathy; hypertrophic 3 antibody; CMD1Y antibody; CMH3 antibody; HTM alpha antibody; HTM-alpha antibody; OTTHUMP00000163688 antibody; sarcomeric tropomyosin kappa antibody; TM2 antibody; Tmpa antibody; TMSA antibody; Tpm-1 antibody; TPM1 antibody; TPM1_HUMAN antibody; tropomyosin 1 (alpha) antibody; tropomyosin 1 (alpha) isoform 1 antibody; tropomyosin 1 (alpha) isoform 2 antibody; tropomyosin 1 (alpha) isoform 3 antibody; tropomyosin 1 (alpha) isoform 4 antibody; tropomyosin 1 (alpha) isoform 5 antibody; tropomyosin 1 (alpha) isoform 6 antibody; tropomyosin 1 (alpha) isoform 7 antibody; Tropomyosin 1 antibody; Tropomyosin alpha 1 chain antibody; Tropomyosin alpha-1 chain antibody; Tropomyosin; skeletal muscle alpha antibody; Tropomyosin-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P09493

Immunogen:Fusion protein of Human TPM1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TPM1

Research Areas:Cardiovascular;Signal transduction