TP53BP2 Antibody - Cat. #: CSB-PA622676ESR2HU

SKU: CSB-PA622676ESR2HU

Size :50ul

Clone Number:

Aliases:53BP2 antibody; Apoptosis stimulating of p53 protein 2 antibody; Apoptosis stimulating protein of p53 2 antibody; Apoptosis-stimulating of p53 protein 2 antibody; ASPP2 antibody; ASPP2_HUMAN antibody; BBP antibody; Bcl2 binding protein antibody; Bcl2-binding protein antibody; NY REN 51 antigen antibody; p53 binding protein 2 antibody; p53-binding protein 2 antibody; p53BP2 antibody; PPP1R13A antibody; Renal carcinoma antigen NY-REN-51 antibody; Tp53bp2 antibody; Tumor protein p53 binding protein 2 antibody; Tumor suppressor p53 binding protein 2 antibody; Tumor suppressor p53-binding protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13625

Immunogen:Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; Recommended dilution: WB:1:200-1:1000

Background:Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TP53BP2

Research Areas:Cell biology