TNNC1 Rabbit Polyclonal Antibody

SKU: BT-AP13111

Size:100μL

Background:Troponin is a central regulatory protein of striated muscle contraction| and together with tropomyosin| is located on the actin filament. Troponin consists of 3 subunits: TnI| which is the inhibitor of actomyosin ATPase; TnT| which contains the binding site for tropomyosin; and TnC| the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI| thus allowing the interaction of actin with myosin| the hydrolysis of ATP| and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Research_area:Signal transduction; Cardiovascular

Target_protein:TNNC1

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:TNNC1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):17710

UniProt accession:Human: P63316; Mouse: P19123

Synonyms:TNNC1

GeneID:Human: 7134; Mouse: 21924