TNIP3 Antibody - Cat. #: CSB-PA197029

SKU: CSB-PA197029

Size :50ul

Clone Number:

Aliases:TNIP3 antibody; ABIN3 antibody; LIND antibody; TNFAIP3-interacting protein 3 antibody; A20-binding inhibitor of NF-kappa-B activation 3 antibody; ABIN-3 antibody; Listeria-induced gene protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96KP6

Immunogen:Synthetic peptide of Human TNIP3

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNIP3

Research Areas:Cardiovascular;Signal transduction