GeneBio Systems
TNFRSF11A Polyclonal Antibody
TNFRSF11A Polyclonal Antibody
SKU:E-AB-64599
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:TNFRSF11A
Target Synonym:TNFRSF11A;CD265;FEO;LOH18CR1;ODFR;OFE;OPTB7;OSTS;PDB2;RANK;TRANCER
Research Areas:Cancer;Cardiovascular;Immunology;Signal Transduction
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse;Rat
Application:IHC;IF
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:Q9Y6Q6
Accession:
Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Concentration:1mg/mL
Immunogen:Recombinant fusion protein of human TNFRSF11A (NP_003830.1).
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method:Affinity purification
Dilution:IHC 1:50-1:100;IF 1:50-1:100
Calculated MW:
ObservedMW:
