TIMM8A Polyclonal Antibody

SKU: E-AB-18755

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: TIMM8A

Target Synonym: DDP 1;DDP;DDP1;Deafness dystonia protein 1;Deafness/dystonia peptide;DFN 1;DFN1;MGC12262;Mitochondrial import inner membrane translocase subunit Tim8 A;MTS;TIM 8A;TIM8;TIM8A;TIM8A;TIMM 8A;timm8a;Translocase of inner mitochondrial membrane 8 homolog A;X linked deafness dystonia protein;X-linked deafness dystonia protein

Research Areas: Neuroscience;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O60220

Accession:

Background: This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome; an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Concentration: 0.84 mg/mL

Immunogen: Fusion protein of human TIMM8A

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: