TFIP11 antibody , Cat. # FNab08633

SKU: FNab08633

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:3H5

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large(IL) and Intron Small(IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.

Immunogen:tuftelin interacting protein 11

Synonyms:STIP

Observed MW:97 kDa

Uniprot ID:Q9UBB9

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:200-1:1000; IHC: 1:50-1:500

Gene ID:24144

Research Area:Neuroscience, Metabolism, Developmental biology