TFE3 antibody , Cat. # FNab08626

SKU: FNab08626

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Immunogen:transcription factor binding to IGHM enhancer 3

Synonyms:bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3

Observed MW:65KD

Uniprot ID:P19532

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP,IHC

Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500

Gene ID:7030

Research Area:Cancer, Immunology, Metabolism