STAB2 Antibody - Cat. #: CSB-PA851979ESR1HU

SKU: CSB-PA851979ESR1HU

Size :50ul

Clone Number:

Aliases:190 kDa form stabilin-2 antibody; 190 kDa hyaluronan receptor for endocytosis antibody; EGF-like antibody; FAS1 EGF-like and X-link domain-containing adhesion molecule 2 antibody; Fasciclin antibody; FEEL-2 antibody; FEEL2 antibody; FELL antibody; FEX2 antibody; HARE antibody; Hyaluronan receptor for endocytosis antibody; laminin-type EGF-like and link domain-containing scavenger receptor 2 antibody; link domain-containing scavenger receptor 2 antibody; STAB-2 antibody; Stab2 antibody; STAB2_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WWQ8

Immunogen:Recombinant Human Stabilin-2 protein (1550-1850AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STAB2

Research Areas:Signal transduction; Stem cells