ST13 Monoclonal Antibody

SKU: BT-MCA4585

Size:100μL

Background:ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

Research_area:Signal transduction

Target_protein:ST13

applications:WB, IHC, ICC

Reactivity:Human, Monkey

Clonality:Monoclonal

Clone ID:3B10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ST13

Immunogen:Purified recombinant fragment of human ST13 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):48kDa

UniProt accession:P50502

Synonyms:HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

GeneID:6767