SPTLC1 Antibody - Cat. #: CSB-PA910014

SKU: CSB-PA910014

Size :50ul

Clone Number:

Aliases:HSAN antibody; HSAN1 antibody; HSN1 antibody; LBC1 antibody; LCB 1 antibody; LCB1 antibody; Long chain base biosynthesis protein 1 antibody; MGC14645 antibody; Serine C palmitoyltransferase antibody; Serine palmitoyl CoA transferase 1 antibody; Serine palmitoyltransferase 1 antibody; Serine palmitoyltransferase long chain base subunit 1 antibody; Serine palmitoyltransferase subunit 1 antibody; Serine-palmitoyl-CoA transferase 1 antibody; SPT 1 antibody; SPT1 antibody; SPTC1_HUMAN antibody; SPTI antibody; SPTLC 1 antibody; SPTLC1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15269

Immunogen:Fusion protein of Human SPTLC1

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SPTLC1

Research Areas:Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction