SPO11 Antibody, FITC conjugated - Cat. #: CSB-PA897506LC01HU

SKU: CSB-PA897506LC01HU

Size :50ug

Clone Number:

Aliases:Cancer/testis antigen 35 antibody; CT35 antibody; Meiotic recombination protein SPO 11 antibody; Meiotic recombination protein SPO11 antibody; MGC39953 antibody; SPATA43 antibody; Spermatogenesis associated 43 antibody; SPO 11 antibody; SPO11 antibody; SPO11 meiotic protein covalently bound to DSB antibody; SPO11 meiotic protein covalently bound to DSB homolog antibody; SPO11 meiotic protein covalently bound to DSB like antibody; SPO11_HUMAN antibody; TOPVIA antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y5K1

Immunogen:Recombinant Human Meiotic recombination protein SPO11 protein (28-109AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SPO11

Research Areas:Epigenetics and Nuclear Signaling; Cell biology