SORD Polyclonal Antibody

SKU: E-AB-53170

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:SORD

Target Synonym:DHSO;L iditol 2 dehydrogenase;L-iditol 2-dehydrogenase;OTTHUMP00000161939;SDH;Sorbitol dehydrogenase 1;Sorbitol dehydrogenase;SORD 1;SORD;SORD1

Research Areas:Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q00796

Accession:

Background:Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Concentration:0.78 mg/mL

Immunogen:Fusion protein of human SORD

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:100

Calculated MW:

ObservedMW: