SOCS7 Antibody, FITC conjugated - Cat. #: CSB-PA022396LC01HU

SKU: CSB-PA022396LC01HU

Size :50ug

Clone Number:

Aliases:Ash and phospholipase C gamma-binding protein antibody; NAP 4 antibody; NAP 4 Fragment antibody; NAP-4 antibody; NAP4 antibody; Nck antibody; Nck Ash and phospholipase C binding protein antibody; Nck Ash and phospholipase C gamma binding protein antibody; Nck associated protein 4 antibody; Nck-associated protein 4 antibody; NCKAP4 antibody; SH2 domain containing SOCS box protein antibody; SOCS 7 antibody; SOCS-7 antibody; SOCS4 antibody; SOCS6 antibody; Socs7 antibody; SOCS7_HUMAN antibody; Suppressor of cytokine signaling 7 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14512

Immunogen:Recombinant Human Suppressor of cytokine signaling 7 protein (6-165AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SOCS7

Research Areas:Signal transduction